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Overexpressed xCT was responsible for the reduction in eumelanin formation in melanocytes and increased production of pheomelanin in the sheep wool, where brown/yellow patches were observed [91]

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Chondrocytes were treated with various doses of IGF-1 for 1 h, stimulated with IL-1β for 24 h, then washed twice with PBS and incubated with 5 μM CellROX Green reagent in PBS at 37°C for 60 min in the dark